Role of primary prophylaxis in preventing variceal bleeding in children with gastroesophageal varices

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Role of endoscopy in primary prophylaxis for esophageal variceal bleeding.

Cirrhosis is the leading cause of portal hypertension in the Western world. From a clinical standpoint, the most significant consequence of portal hypertension is the development of esophageal varices. Despite the many advances in the management of variceal bleeding, it remains a life-threatening complication of portal hypertension. Primary prophylaxis to prevent the first bleeding episode in p...

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Portal hypertension: pre-primary and primary prophylaxis of variceal bleeding.

In liver cirrhosis, variceal bleeding is the last in a chain of events initiated by the increase in portal pressure (estimated in clinical practice by the hepatic venous pressure gradient). When hepatic venous pressure gradient goes above 10 mmHg the patient is at risk of developing varices, and when hepatic venous pressure gradient reaches 12 mmHg variceal bleeding might develop. Currently, th...

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Endoscopic band ligation versus propranolol for the primary prophylaxis of variceal bleeding in cirrhotic patients with high risk esophageal varices.

BACKGROUND Gastroesophageal variceal bleeding is a common complication of portal hypertension. Current guidelines recommend thorn-blockers for primary prophylaxis. However, evidence suggests that endoscopic variceal ligation (EVL) reduce bleeding episodes. AIMS To compare endoscopic EVL with propranolol (PPL) for primary prophylaxis of variceal bleeding. METHODS We conducted a randomized co...

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Variceal Bleeding Prophylaxis: Variceal Banding or Propranolol

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ژورنال

عنوان ژورنال: Pediatrics & Neonatology

سال: 2021

ISSN: 1875-9572

DOI: 10.1016/j.pedneo.2021.01.002